Bridge Rectifier

[emj12]

What are the draw backs (if any) of using a bridge rectifier in a guitar amp?

Is there anything I will have to do differently aside from the way I bulid the power supply?

[defaced]

Some more details about what you're building and your other build options would be helpful.  You mention draw backs, that usually implies there are other options which are "better", but without more detail about what those options are for your project we can't give you a meaningful reply. 

But to directly answer your question: none, it's done all the time. If the PT was designed for it, then build with it.  If the PT wasn't designed for it, don't use it.

[a soBer Newt]

Are you asking about "tube sag"  were a bridge rectifier has a faster recovery versus a tube rectifier?  I have talked with Fred Forssell about this, we were talking linear supplies vs. switching supplies and he say that linear supplies sound better to him vs switching.  So yea it may make a difference but not sure if it will be audible.